Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (299 aa)    
Predicted Functional Partners:
thrC
Threonine synthase.
 
 0.999
hom
Homoserine dehydrogenase.
 
 0.999
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
  
 0.936
mccB
Cystathionine gamma-lyase.
  
 
 0.930
metC_1
Cystathionine beta-lyase MetC.
  
 
 0.930
metC_2
Cystathionine beta-lyase.
  
 
 0.930
yclM
Aspartokinase 3; Belongs to the aspartokinase family.
 
 0.924
lysC
Aspartate kinase Ask_LysC; Belongs to the aspartokinase family.
 
 0.923
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.913
yitJ
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.
  
 
 0.903
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
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