| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| sigE_1 | sigF_2 | CLSAP_12270 | CLSAP_12280 | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.775 |
| sigE_1 | spo0A | CLSAP_12270 | CLSAP_25020 | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.853 |
| sigE_1 | spoIIAB_1 | CLSAP_12270 | CLSAP_09340 | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.782 |
| sigE_1 | spoIIID | CLSAP_12270 | CLSAP_06330 | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein D. | 0.820 |
| sigE_1 | spoIIR | CLSAP_12270 | CLSAP_06020 | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein SpoIIR. | 0.810 |
| sigE_1 | spoIVA | CLSAP_12270 | CLSAP_12420 | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.794 |
| sigE_1 | spoVAC1 | CLSAP_12270 | CLSAP_09360 | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SpoVA protein. | 0.774 |
| sigE_1 | spoVAD_1 | CLSAP_12270 | CLSAP_09370 | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation protein AD. | 0.773 |
| sigE_1 | spoVAEB1 | CLSAP_12270 | CLSAP_09380 | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SpoVA protein. | 0.773 |
| sigE_1 | spoVT_2 | CLSAP_12270 | CLSAP_17250 | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation protein T. | 0.693 |
| sigF_2 | sigE_1 | CLSAP_12280 | CLSAP_12270 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | RNA polymerase sigma-E factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.775 |
| sigF_2 | spo0A | CLSAP_12280 | CLSAP_25020 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.941 |
| sigF_2 | spoIIAB_1 | CLSAP_12280 | CLSAP_09340 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.921 |
| sigF_2 | spoIIID | CLSAP_12280 | CLSAP_06330 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein D. | 0.900 |
| sigF_2 | spoIIR | CLSAP_12280 | CLSAP_06020 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein SpoIIR. | 0.825 |
| sigF_2 | spoIVA | CLSAP_12280 | CLSAP_12420 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.837 |
| sigF_2 | spoVAC1 | CLSAP_12280 | CLSAP_09360 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SpoVA protein. | 0.774 |
| sigF_2 | spoVAD_1 | CLSAP_12280 | CLSAP_09370 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation protein AD. | 0.786 |
| sigF_2 | spoVAEB1 | CLSAP_12280 | CLSAP_09380 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SpoVA protein. | 0.773 |
| sigF_2 | spoVT_2 | CLSAP_12280 | CLSAP_17250 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation protein T. | 0.718 |