| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adeC | apt | CLSAP_14450 | CLSAP_23840 | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.988 |
| adeC | deoD_1 | CLSAP_14450 | CLSAP_16270 | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Purine nucleoside phosphorylase DeoD-type. | 0.963 |
| adeC | deoD_2 | CLSAP_14450 | CLSAP_44490 | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Purine nucleoside phosphorylase DeoD-type. | 0.963 |
| adeC | guaA | CLSAP_14450 | CLSAP_04580 | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.633 |
| adeC | ppnP | CLSAP_14450 | CLSAP_32820 | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.900 |
| adeC | punA | CLSAP_14450 | CLSAP_16010 | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.972 |
| adeC | xpt | CLSAP_14450 | CLSAP_27690 | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.880 |
| apt | adeC | CLSAP_23840 | CLSAP_14450 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.988 |
| apt | deoD_1 | CLSAP_23840 | CLSAP_16270 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase DeoD-type. | 0.972 |
| apt | deoD_2 | CLSAP_23840 | CLSAP_44490 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase DeoD-type. | 0.972 |
| apt | gmk | CLSAP_23840 | CLSAP_12460 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.972 |
| apt | guaA | CLSAP_23840 | CLSAP_04580 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.990 |
| apt | ppnP | CLSAP_23840 | CLSAP_32820 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.982 |
| apt | punA | CLSAP_23840 | CLSAP_16010 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.988 |
| apt | purB | CLSAP_23840 | CLSAP_13260 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.971 |
| apt | purH | CLSAP_23840 | CLSAP_11560 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Bifunctional purine biosynthesis protein PurH. | 0.976 |
| apt | xpt | CLSAP_23840 | CLSAP_27690 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.954 |
| deoD_1 | adeC | CLSAP_16270 | CLSAP_14450 | Purine nucleoside phosphorylase DeoD-type. | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.963 |
| deoD_1 | apt | CLSAP_16270 | CLSAP_23840 | Purine nucleoside phosphorylase DeoD-type. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.972 |
| deoD_1 | deoD_2 | CLSAP_16270 | CLSAP_44490 | Purine nucleoside phosphorylase DeoD-type. | Purine nucleoside phosphorylase DeoD-type. | 0.904 |