Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adhE_4Aldehyde-alcohol dehydrogenase. (388 aa)    
Predicted Functional Partners:
adhE_6
Aldehyde-alcohol dehydrogenase.
 0.961
adhE_2
Aldehyde-alcohol dehydrogenase.
 0.931
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.924
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.924
korA
2-oxoglutarate oxidoreductase subunit KorA.
  
 
 0.689
lacZ
Beta-galactosidase; Belongs to the glycosyl hydrolase 2 family.
   
  
 0.659
mdlD
NAD(P)-dependent benzaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.616
pflA_1
Pyruvate formate-lyase 1-activating enzyme; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
 
 0.594
queE_1
7-carboxy-7-deazaguanine synthase.
  
 
 0.594
pflA_2
Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 
 0.594
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
Server load: low (40%) [HD]