Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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[Homology]
Score
queD6-pyruvoyl tetrahydropterin synthase. (142 aa)    
Predicted Functional Partners:
folE
GTP cyclohydrolase 1.
 
 
 0.999
queE_2
7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.999
queC_2
7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
 
  
 0.991
queF
NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
 
 0.985
queC_1
7-cyano-7-deazaguanine synthase.
  
  
 0.846
sulD
Bifunctional folate synthesis protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
 
 0.843
gltB_2
Ferredoxin-dependent glutamate synthase 1.
  
 
  0.604
hisI
Histidine biosynthesis bifunctional protein HisIE; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
     
 0.586
hisE
phosphoribosyl-ATP pyrophosphatase.
     
 0.586
cysS_1
cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.582
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
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