Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
patBCystathionine beta-lyase PatB. (396 aa)    
Predicted Functional Partners:
metH_1
Methionine synthase.
     
 0.983
metH_2
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.983
mccB
Cystathionine gamma-lyase.
 
 
 0.978
metC_1
Cystathionine beta-lyase MetC.
 
 
 0.977
metC_2
Cystathionine beta-lyase.
 
 
 0.977
yitJ
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.
    
 0.973
mdeA
Methionine gamma-lyase.
   
 0.967
cysK1
O-acetylserine sulfhydrylase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.950
cysK_2
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.950
mccA_1
O-acetylserine dependent cystathionine beta-synthase.
    
 0.946
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
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