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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
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alsS_2Acetolactate synthase; Belongs to the TPP enzyme family. (556 aa)    
Predicted Functional Partners:
ilvH
Acetolactate synthase small subunit.
 
 0.995
ilvC_1
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.995
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.993
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.993
ilvN
Acetolactate synthase isozyme 1 small subunit.
 
 0.992
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.982
tdcB
L-threonine dehydratase catabolic TdcB.
 
 0.982
korA
2-oxoglutarate oxidoreductase subunit KorA.
  
 
 0.971
korB
2-oxoglutarate oxidoreductase subunit KorB.
  
 
 0.961
leuA_2
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.922
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
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