Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
manRTranscriptional regulator ManR. (799 aa)    
Predicted Functional Partners:
manP
PTS system mannose-specific EIIBCA component.
 
 
 0.933
fruA_3
PTS system fructose-specific EIIBC component.
 
 
 0.921
fruA_2
PTS system fructose-specific EIIABC component.
 
 
0.907
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 
 0.783
bglF_4
PTS system beta-glucoside-specific EIIBCA component.
 
 0.746
bglF_3
PTS system beta-glucoside-specific EIIBCA component.
 
 0.744
bglF_6
PTS system beta-glucoside-specific EIIBCA component.
 
 0.742
bglF_8
PTS system beta-glucoside-specific EIIBCA component.
 
 0.742
bglF_7
PTS system beta-glucoside-specific EIIBCA component.
 
 0.741
bglF_9
PTS system beta-glucoside-specific EIIBCA component.
 
 0.741
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
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