| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQR96643.1 | nudL | CLSAP_39670 | CLSAP_39680 | Hypothetical protein. | Putative nudix hydrolase NudL. | 0.689 |
| birA | dapF | CLSAP_11020 | CLSAP_24660 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.488 |
| birA | nrdE2 | CLSAP_11020 | CLSAP_02280 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Ribonucleoside-diphosphate reductase subunit alpha 2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.519 |
| birA | nudL | CLSAP_11020 | CLSAP_39680 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Putative nudix hydrolase NudL. | 0.806 |
| cshA_2 | dbpA | CLSAP_27840 | CLSAP_31230 | DEAD-box ATP-dependent RNA helicase CshA. | ATP-dependent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. | 0.908 |
| cshA_2 | nnr | CLSAP_27840 | CLSAP_52780 | DEAD-box ATP-dependent RNA helicase CshA. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to al [...] | 0.759 |
| cshA_2 | nudL | CLSAP_27840 | CLSAP_39680 | DEAD-box ATP-dependent RNA helicase CshA. | Putative nudix hydrolase NudL. | 0.595 |
| cshA_2 | pyrG | CLSAP_27840 | CLSAP_06060 | DEAD-box ATP-dependent RNA helicase CshA. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.613 |
| cshA_2 | rnr | CLSAP_27840 | CLSAP_48580 | DEAD-box ATP-dependent RNA helicase CshA. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.558 |
| cshA_3 | dbpA | CLSAP_31240 | CLSAP_31230 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | ATP-dependent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. | 0.604 |
| cshA_3 | nnr | CLSAP_31240 | CLSAP_52780 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to al [...] | 0.759 |
| cshA_3 | nudL | CLSAP_31240 | CLSAP_39680 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | Putative nudix hydrolase NudL. | 0.595 |
| cshA_3 | pyrG | CLSAP_31240 | CLSAP_06060 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.613 |
| cshA_3 | rnr | CLSAP_31240 | CLSAP_48580 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.558 |
| dapF | birA | CLSAP_24660 | CLSAP_11020 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.488 |
| dapF | nudL | CLSAP_24660 | CLSAP_39680 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Putative nudix hydrolase NudL. | 0.604 |
| dbpA | cshA_2 | CLSAP_31230 | CLSAP_27840 | ATP-dependent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. | DEAD-box ATP-dependent RNA helicase CshA. | 0.908 |
| dbpA | cshA_3 | CLSAP_31230 | CLSAP_31240 | ATP-dependent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | 0.604 |
| dbpA | nnr | CLSAP_31230 | CLSAP_52780 | ATP-dependent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to al [...] | 0.759 |
| dbpA | nudL | CLSAP_31230 | CLSAP_39680 | ATP-dependent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. | Putative nudix hydrolase NudL. | 0.595 |