Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mdh_2NAD-dependent methanol dehydrogenase. (381 aa)    
Predicted Functional Partners:
adhE_2
Aldehyde-alcohol dehydrogenase.
 0.934
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.924
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.924
adhE_6
Aldehyde-alcohol dehydrogenase.
 0.871
ulaF_3
L-ribulose-5-phosphate 4-epimerase UlaF.
  
 
 0.833
fldZ_3
2-enoate reductase FldZ.
  
 
 0.732
adhE_5
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
0.696
korA
2-oxoglutarate oxidoreductase subunit KorA.
  
 
 0.689
adhE_3
Aldehyde-alcohol dehydrogenase.
 
0.670
cfiB_2
2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.647
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
Server load: low (30%) [HD]