Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rsbVanti-sigma-B factor antagonist; Belongs to the anti-sigma-factor antagonist family. (94 aa)    
Predicted Functional Partners:
spoIIAB_2
Anti-sigma F factor.
 
 
 0.991
spoIIAB_1
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.950
rsbP
Phosphoserine phosphatase RsbP.
 
 
 0.944
barA_2
Signal transduction histidine-protein kinase BarA.
 
  
 0.930
fliN
Flagellar motor switch protein FliN.
  
   0.924
flgE
Flagellar hook protein FlgE.
   
    0.904
fliG
Flagellar motor switch protein FliG.
  
   0.880
luxQ_1
Autoinducer 2 sensor kinase/phosphatase LuxQ.
 
  
 0.867
flgB
Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
  
    0.853
fliF
Flagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
    0.816
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.