| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQR95906.1 | cdr_2 | CLSAP_32220 | CLSAP_30790 | Hypothetical protein. | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | 0.647 |
| AQR95906.1 | grpE | CLSAP_32220 | CLSAP_09560 | Hypothetical protein. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.483 |
| AQR95906.1 | trxA_3 | CLSAP_32220 | CLSAP_49600 | Hypothetical protein. | Thioredoxin; Belongs to the thioredoxin family. | 0.618 |
| cdr_2 | AQR95906.1 | CLSAP_30790 | CLSAP_32220 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Hypothetical protein. | 0.647 |
| cdr_2 | groL | CLSAP_30790 | CLSAP_04550 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.582 |
| cdr_2 | grpE | CLSAP_30790 | CLSAP_09560 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.604 |
| cdr_2 | hcnB_3 | CLSAP_30790 | CLSAP_46780 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Hydrogen cyanide synthase subunit HcnB. | 0.628 |
| cdr_2 | trxA_3 | CLSAP_30790 | CLSAP_49600 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Thioredoxin; Belongs to the thioredoxin family. | 0.621 |
| groL | cdr_2 | CLSAP_04550 | CLSAP_30790 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | 0.582 |
| groL | grpE | CLSAP_04550 | CLSAP_09560 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.994 |
| groL | hcnB_3 | CLSAP_04550 | CLSAP_46780 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Hydrogen cyanide synthase subunit HcnB. | 0.409 |
| groL | htpG | CLSAP_04550 | CLSAP_16040 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Chaperone protein HtpG. | 0.960 |
| groL | nrdE2 | CLSAP_04550 | CLSAP_02280 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Ribonucleoside-diphosphate reductase subunit alpha 2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.435 |
| groL | trxA_3 | CLSAP_04550 | CLSAP_49600 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Thioredoxin; Belongs to the thioredoxin family. | 0.715 |
| grpE | AQR95906.1 | CLSAP_09560 | CLSAP_32220 | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Hypothetical protein. | 0.483 |
| grpE | cdr_2 | CLSAP_09560 | CLSAP_30790 | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | 0.604 |
| grpE | groL | CLSAP_09560 | CLSAP_04550 | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.994 |
| grpE | hcnB_3 | CLSAP_09560 | CLSAP_46780 | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Hydrogen cyanide synthase subunit HcnB. | 0.431 |
| grpE | htpG | CLSAP_09560 | CLSAP_16040 | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Chaperone protein HtpG. | 0.883 |
| grpE | nrdE2 | CLSAP_09560 | CLSAP_02280 | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Ribonucleoside-diphosphate reductase subunit alpha 2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.680 |
