STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serB3-phosphoserine phosphatase; Pfam match to PF00702 Hydrolase, score 77.7, E-value 8.1E-022. (208 aa)    
Predicted Functional Partners:
hisI
Bifunctional phosphoribosyl-AMP cyclohydrolase/ phosphoribosyl-ATP pyrophosphohydrolase; Pfam matches to PF01502 PRA-CH, score 173.5, E-value 4.8E-049, and to PF01503 PRA-PH, score 98.2, E-value 2.2E-026; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.975
glyA1
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.923
glyA2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.923
ilvA
Threonine deaminase; Pfam match to PF00291 PALP, score 266.2, E-value 6.1E-077.
    
 0.914
trpB1
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
 
 0.913
trpB2
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
 
 0.913
pssA
CDP-diacylglycerol--serine O-phosphatidyltransferase; Pfam match to PF01066 CDP-OH_P_transf, score 44.3, E-value 3.8E-010; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.905
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.901
cysE
Serine acetyltransferase.
 
  
 0.873
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
   
 
 0.867
Your Current Organism:
Arcobacter butzleri
NCBI taxonomy Id: 367737
Other names: A. butzleri RM4018, Arcobacter butzleri RM4018, Arcobacter butzleri str. RM4018, Arcobacter butzleri strain RM4018
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.