STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxAPyridoxal phosphate biosynthetic protein A; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (311 aa)    
Predicted Functional Partners:
pdxJ
Pyridoxal phosphate biosynthesis protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
 
 
 0.980
Abu_0652
Conserved hypothetical protein; Pfam match to PF05036 SPOR, score 32.8, E-value 3.7E-009.
       0.780
Abu_0648
Conserved hypothetical protein.
       0.779
trpE
Anthranilate synthase, component I; Pfam matches to PF00425 Chorismate_bind, score 421.5, E-value 1.1E-123, and to PF04715 Anth_synt_I_N, score 50.4, E-value 1.2E-014.
       0.775
lysS
lysyl-tRNA synthetase; Pfam matches to PF00152 tRNA-synt_2, score 380.5, E-value 2.4E-111, and to PF01336 tRNA_anti, score 65.5, E-value 1.6E-016; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.708
glyA1
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.692
Abu_0655
Pfam match to PF02674 Colicin_V, score 95.9, E-value 1.1E-025.
       0.659
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
       0.603
spoT
Bifunctional ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
  
 0.571
rpoZ
DNA-directed RNA polymerase, omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
       0.556
Your Current Organism:
Arcobacter butzleri
NCBI taxonomy Id: 367737
Other names: A. butzleri RM4018, Arcobacter butzleri RM4018, Arcobacter butzleri str. RM4018, Arcobacter butzleri strain RM4018
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