node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Abu_0661 | glmU | Abu_0661 | Abu_2204 | UDP-hexose dehydrogenase; Pfam matches to PF03721 UDPG_MGDP_dh_N, score 239.8, E-value 5.3E-069, and to PF00984 UDPG_MGDP_dh, score 149.4, E-value 8.5E-042, and to PF03720 UDPG_MGDP_dh_C, score 98.5, E-value 1.9E-026; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.914 |
Abu_0661 | lpxA | Abu_0661 | Abu_2215 | UDP-hexose dehydrogenase; Pfam matches to PF03721 UDPG_MGDP_dh_N, score 239.8, E-value 5.3E-069, and to PF00984 UDPG_MGDP_dh, score 149.4, E-value 8.5E-042, and to PF03720 UDPG_MGDP_dh_C, score 98.5, E-value 1.9E-026; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.821 |
Abu_0661 | murA | Abu_0661 | Abu_1843 | UDP-hexose dehydrogenase; Pfam matches to PF03721 UDPG_MGDP_dh_N, score 239.8, E-value 5.3E-069, and to PF00984 UDPG_MGDP_dh, score 149.4, E-value 8.5E-042, and to PF03720 UDPG_MGDP_dh_C, score 98.5, E-value 1.9E-026; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.905 |
Abu_0661 | pseB | Abu_0661 | Abu_2243 | UDP-hexose dehydrogenase; Pfam matches to PF03721 UDPG_MGDP_dh_N, score 239.8, E-value 5.3E-069, and to PF00984 UDPG_MGDP_dh, score 149.4, E-value 8.5E-042, and to PF03720 UDPG_MGDP_dh_C, score 98.5, E-value 1.9E-026; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | UDP GlcNAc dehydratase/reductase PseB, putative; Pfam match to PF02719 Polysacc_synt_2, score 540, E-value 2.3E-159. | 0.922 |
Abu_1842 | murA | Abu_1842 | Abu_1843 | Hypothetical protein. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.786 |
glmU | Abu_0661 | Abu_2204 | Abu_0661 | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | UDP-hexose dehydrogenase; Pfam matches to PF03721 UDPG_MGDP_dh_N, score 239.8, E-value 5.3E-069, and to PF00984 UDPG_MGDP_dh, score 149.4, E-value 8.5E-042, and to PF03720 UDPG_MGDP_dh_C, score 98.5, E-value 1.9E-026; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.914 |
glmU | lpxA | Abu_2204 | Abu_2215 | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.841 |
glmU | murA | Abu_2204 | Abu_1843 | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.941 |
glmU | murC | Abu_2204 | Abu_0234 | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.498 |
glmU | murE | Abu_2204 | Abu_0522 | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.746 |
glmU | murG | Abu_2204 | Abu_1909 | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.431 |
glmU | pseB | Abu_2204 | Abu_2243 | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | UDP GlcNAc dehydratase/reductase PseB, putative; Pfam match to PF02719 Polysacc_synt_2, score 540, E-value 2.3E-159. | 0.910 |
lpxA | Abu_0661 | Abu_2215 | Abu_0661 | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-hexose dehydrogenase; Pfam matches to PF03721 UDPG_MGDP_dh_N, score 239.8, E-value 5.3E-069, and to PF00984 UDPG_MGDP_dh, score 149.4, E-value 8.5E-042, and to PF03720 UDPG_MGDP_dh_C, score 98.5, E-value 1.9E-026; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.821 |
lpxA | glmU | Abu_2215 | Abu_2204 | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.841 |
lpxA | murA | Abu_2215 | Abu_1843 | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.883 |
lpxA | pseB | Abu_2215 | Abu_2243 | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP GlcNAc dehydratase/reductase PseB, putative; Pfam match to PF02719 Polysacc_synt_2, score 540, E-value 2.3E-159. | 0.810 |
murA | Abu_0661 | Abu_1843 | Abu_0661 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-hexose dehydrogenase; Pfam matches to PF03721 UDPG_MGDP_dh_N, score 239.8, E-value 5.3E-069, and to PF00984 UDPG_MGDP_dh, score 149.4, E-value 8.5E-042, and to PF03720 UDPG_MGDP_dh_C, score 98.5, E-value 1.9E-026; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.905 |
murA | Abu_1842 | Abu_1843 | Abu_1842 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Hypothetical protein. | 0.786 |
murA | glmU | Abu_1843 | Abu_2204 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.941 |
murA | lpxA | Abu_1843 | Abu_2215 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.883 |