Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BAD_0004Hypothetical protein; Orthologue of BL0636. (161 aa)    
Predicted Functional Partners:
recF
Recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
  
  
 0.828
dnaN
DNA polymerase III, b subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation [...]
     
 0.738
BAD_0861
Hypothetical protein; COG family: DNA polymerase III delta subunit; Orthologue of BL1454.
  
   
 0.716
BAD_0029
Hypothetical protein; Orthologue of BL0598.
  
     0.706
BAD_0249
Hypothetical protein; COG family: regulator of polyketide synthaseexpression; Orthologue of BL1531.
  
     0.676
BAD_1613
COG family: protein-disulfide isomerase; Orthologue of BL0659.
  
     0.663
BAD_0007
Hypothetical protein; Orthologue of BL0633.
 
     0.638
BAD_0630
Hypothetical protein; COG family: uncharacterized Bcr_ stimulatesglucose-6-P dehydrogenase activity; Orthologue of BL0441.
  
     0.620
BAD_0913
Hypothetical protein; Orthologue of BL1050.
  
     0.610
BAD_0173
Hypothetical protein; COG family: phosphoglyceratemutase_fructose-2_6-bisphosphatase; Orthologue of BL0474; PFAM_ID: PGAM.
  
     0.607
Your Current Organism:
Bifidobacterium adolescentis
NCBI taxonomy Id: 367928
Other names: B. adolescentis ATCC 15703, Bifidobacterium adolescentis ATCC 15703, Bifidobacterium adolescentis str. ATCC 15703, Bifidobacterium adolescentis strain ATCC 15703
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