Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
asdAspartate-semialdehyde dehydrogenase; Catalyzes the formation of aspartate semialdehydefrom aspartyl phosphate; Orthologue of BL0492; Belongs to the aspartate-semialdehyde dehydrogenase family. (364 aa)    
Predicted Functional Partners:
thrA
COG family: homoserine dehydrogenase; Orthologue of BL1274; PFAM_ID: ACT; PFAM_ID: Homoserine_dh.
  
 0.985
askA
Aspartokinase alpha subunit; AskA; COG family:aspartokinases; Orthologue of BL0494; PFAM_ID: aakinase; Belongs to the aspartokinase family.
  
 
 0.982
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 
 0.965
askB
Aspartokinase beta subunit; AskB; COG family:aspartokinases; Orthologue of BL0493; PFAM_ID: ACT.
  
 
 0.879
lysA
Probable diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
 
 0.755
pgk
Phosphoglycerate kinase; Catalyzes the formation of 3-phospho-D-glyceroylphosphate from 3-phospho-D-glycerate; Orthologue of BL0707; Belongs to the phosphoglycerate kinase family.
  
 0.710
gltB
Glutamate synthase [NADPH] large subunit; Orthologue of Rv3859c_BL0834; ProbablegltB_ ferredoxin-dependent glutamate synthase largesubunit (EC 1.4.1.13).
  
  
 0.661
ilvN
Acetolactate synthase small subunit; Orthologue of BL0297; With IlvI Catalyzes the formation of 2-acetolactatefrom pyruvate_ the small subunit is required for fullactivity and valine sensitivity.
  
 
 0.636
BAD_0142
Hypothetical protein; Orthologue of BL0491.
       0.632
ribD
Riboflavin biosynthesis protein RibD; Orthologue of SAK_0872; identified by similarity to SP:P17618.
    
 
 0.626
Your Current Organism:
Bifidobacterium adolescentis
NCBI taxonomy Id: 367928
Other names: B. adolescentis ATCC 15703, Bifidobacterium adolescentis ATCC 15703, Bifidobacterium adolescentis str. ATCC 15703, Bifidobacterium adolescentis strain ATCC 15703
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