STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkPhosphoglycerate kinase; Catalyzes the formation of 3-phospho-D-glyceroylphosphate from 3-phospho-D-glycerate; Orthologue of BL0707; Belongs to the phosphoglycerate kinase family. (401 aa)    
Predicted Functional Partners:
tpi
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 0.999
gap
COG family:glyceraldehyde-3-phosphatedehydrogenase_erythrose- 4-phosphate dehydrogenase; Orthologue of BL1363; PFAM_ID: GpdH; PFAM_ID: gpdh_C; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.999
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.997
gpm
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.992
pgi
Glucose-6-phosphate isomerase; Orthologue of Rv0946c_BL0279; Probable pgi_glucose-6-phosphate isomerase (EC 5.3.1.9); Belongs to the GPI family.
  
 0.973
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 0.955
pyk
COG family: pyruvate kinase; Orthologue of BL0988; PFAM_ID: PK; Belongs to the pyruvate kinase family.
 
 
 0.929
BAD_0867
COG family: phosphoglyceratemutase_fructose-2_6-bisphosphatase; Orthologue of BL1447; PFAM_ID: PGAM.
     
 0.899
tkt
Transketolase; Catalyzes the formation of ribose 5-phosphate andxylulose 5-phosphate from sedoheptulose 7-phosphate andglyxeraldehyde 3-phosphate; Orthologue of Rv1449c_BL0716; Belongs to the transketolase family.
  
 0.818
BAD_0024
Narrowly conserved hypothetical protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
  
 
 0.809
Your Current Organism:
Bifidobacterium adolescentis
NCBI taxonomy Id: 367928
Other names: B. adolescentis ATCC 15703, Bifidobacterium adolescentis ATCC 15703, Bifidobacterium adolescentis str. ATCC 15703, Bifidobacterium adolescentis strain ATCC 15703
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