| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BAD_0228 | BAD_1027 | BAD_0228 | BAD_1027 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | CinA-like protein; COG family: uncharacterized protein (competence-and mitomycin-induced); Orthologue of BL1413; PFAM_ID: CinA; Belongs to the CinA family. | 0.883 |
| BAD_0228 | BAD_1346 | BAD_0228 | BAD_1346 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein; COG family: NTP pyrophosphohydrolases containing aZn-finger_ probably nucleic-acid-binding; Orthologue of BL1222; PFAM_ID: NUDIX. | 0.860 |
| BAD_0228 | BAD_1569 | BAD_0228 | BAD_1569 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Sir2-type regulatory protein; COG family: NAD-dependent protein deacetylases_Sir2 family; Orthologue of BL1528; PFAM_ID: SIR2. | 0.506 |
| BAD_0228 | nadD | BAD_0228 | BAD_0899 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Possible nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.938 |
| BAD_0228 | nadE | BAD_0228 | BAD_0994 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.850 |
| BAD_0900 | nadD | BAD_0900 | BAD_0899 | Hypothetical protein; Orthologue of BL1033. | Possible nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.799 |
| BAD_0900 | proA | BAD_0900 | BAD_0901 | Hypothetical protein; Orthologue of BL1033. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.771 |
| BAD_1027 | BAD_0228 | BAD_1027 | BAD_0228 | CinA-like protein; COG family: uncharacterized protein (competence-and mitomycin-induced); Orthologue of BL1413; PFAM_ID: CinA; Belongs to the CinA family. | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.883 |
| BAD_1027 | BAD_1346 | BAD_1027 | BAD_1346 | CinA-like protein; COG family: uncharacterized protein (competence-and mitomycin-induced); Orthologue of BL1413; PFAM_ID: CinA; Belongs to the CinA family. | Hypothetical protein; COG family: NTP pyrophosphohydrolases containing aZn-finger_ probably nucleic-acid-binding; Orthologue of BL1222; PFAM_ID: NUDIX. | 0.857 |
| BAD_1027 | nadD | BAD_1027 | BAD_0899 | CinA-like protein; COG family: uncharacterized protein (competence-and mitomycin-induced); Orthologue of BL1413; PFAM_ID: CinA; Belongs to the CinA family. | Possible nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.926 |
| BAD_1027 | nadE | BAD_1027 | BAD_0994 | CinA-like protein; COG family: uncharacterized protein (competence-and mitomycin-induced); Orthologue of BL1413; PFAM_ID: CinA; Belongs to the CinA family. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.899 |
| BAD_1027 | ppnK | BAD_1027 | BAD_0908 | CinA-like protein; COG family: uncharacterized protein (competence-and mitomycin-induced); Orthologue of BL1413; PFAM_ID: CinA; Belongs to the CinA family. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.425 |
| BAD_1346 | BAD_0228 | BAD_1346 | BAD_0228 | Hypothetical protein; COG family: NTP pyrophosphohydrolases containing aZn-finger_ probably nucleic-acid-binding; Orthologue of BL1222; PFAM_ID: NUDIX. | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.860 |
| BAD_1346 | BAD_1027 | BAD_1346 | BAD_1027 | Hypothetical protein; COG family: NTP pyrophosphohydrolases containing aZn-finger_ probably nucleic-acid-binding; Orthologue of BL1222; PFAM_ID: NUDIX. | CinA-like protein; COG family: uncharacterized protein (competence-and mitomycin-induced); Orthologue of BL1413; PFAM_ID: CinA; Belongs to the CinA family. | 0.857 |
| BAD_1346 | BAD_1569 | BAD_1346 | BAD_1569 | Hypothetical protein; COG family: NTP pyrophosphohydrolases containing aZn-finger_ probably nucleic-acid-binding; Orthologue of BL1222; PFAM_ID: NUDIX. | Sir2-type regulatory protein; COG family: NAD-dependent protein deacetylases_Sir2 family; Orthologue of BL1528; PFAM_ID: SIR2. | 0.868 |
| BAD_1346 | nadD | BAD_1346 | BAD_0899 | Hypothetical protein; COG family: NTP pyrophosphohydrolases containing aZn-finger_ probably nucleic-acid-binding; Orthologue of BL1222; PFAM_ID: NUDIX. | Possible nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.858 |
| BAD_1346 | nadE | BAD_1346 | BAD_0994 | Hypothetical protein; COG family: NTP pyrophosphohydrolases containing aZn-finger_ probably nucleic-acid-binding; Orthologue of BL1222; PFAM_ID: NUDIX. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.927 |
| BAD_1346 | pntA | BAD_1346 | BAD_0725 | Hypothetical protein; COG family: NTP pyrophosphohydrolases containing aZn-finger_ probably nucleic-acid-binding; Orthologue of BL1222; PFAM_ID: NUDIX. | COG family: NAD_NADP transhydrogenase alphasubunit; Orthologue of BL0857; PFAM_ID: AlaDh_PNT; Pyridine nucleotide transhydrogenase subunit alpha1. | 0.857 |
| BAD_1346 | pntB | BAD_1346 | BAD_0726 | Hypothetical protein; COG family: NTP pyrophosphohydrolases containing aZn-finger_ probably nucleic-acid-binding; Orthologue of BL1222; PFAM_ID: NUDIX. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.857 |
| BAD_1346 | ppnK | BAD_1346 | BAD_0908 | Hypothetical protein; COG family: NTP pyrophosphohydrolases containing aZn-finger_ probably nucleic-acid-binding; Orthologue of BL1222; PFAM_ID: NUDIX. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.857 |