Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pflFormate acetyltransferase; Orthologue of BL0951_HI0180. (791 aa)    
Predicted Functional Partners:
pflA
Pyruvate formate-lyase 1 activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
 
 0.992
BAD_0319
Acetaldehyde dehydrogenase; Orthologue of ECs1741; Similar to ADHE_ECOLI gi|1787493 (conserved in Escherichia coli K-12); In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.970
pta
Phosphate acetyltransferase; COG family:phosphotransacetylase; Orthologue of BL0968; PFAM_ID: PTA_PTB; Phosphotransacetylase.
   
 
 0.936
ldh2
L-lactate dehydrogenase 2; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.878
pyk
COG family: pyruvate kinase; Orthologue of BL0988; PFAM_ID: PK; Belongs to the pyruvate kinase family.
   
 
 0.877
ilvB1
Acetohydroxy-acid synthase; Catalyzes the formation of 2-acetolactate frompyruvate; Orthologue of Rv3003c_BL0296.
     
 0.869
pdhD
COG family: dihydrolipoamidedehydrogenase_glutathio ne oxidoreductase and relatedenzymes; Orthologue of BL1074; PFAM_ID: pyr_redox.
     
 0.868
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
     
 0.866
gltA2
COG family: citrate synthase; Orthologue of BL1733; Belongs to the citrate synthase family.
     
 0.863
tdcB
COG family: threonine dehydratase; Orthologue of BL1527; PFAM_ID: ACT; PFAM_ID:PALP.
   
 
 0.862
Your Current Organism:
Bifidobacterium adolescentis
NCBI taxonomy Id: 367928
Other names: B. adolescentis ATCC 15703, Bifidobacterium adolescentis ATCC 15703, Bifidobacterium adolescentis str. ATCC 15703, Bifidobacterium adolescentis strain ATCC 15703
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