Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lysX_1lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)    
Predicted Functional Partners:
argS
arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.948
ileS
isoleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.931
leuS_1
leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.931
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
  
 0.927
lysS
lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
0.916
lysX_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.916
ANO23273.1
methionine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.898
guaA
Glutamine-hydrolyzing GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.874
rpsB
30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.850
gltX
glutamate--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.844
Your Current Organism:
Mycobacteroides abscessus
NCBI taxonomy Id: 36809
Other names: ATCC 19977, CCUG 20993, CIP 104536, DSM 44196, JCM 13569, M. abscessus, Mycobacterium abscessus, Mycobacterium chelonae subsp. abscessus, Mycobacterium chelonei subsp. abscessus, NCTC 13031, strain Hauduroy L948
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