Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (474 aa)    
Predicted Functional Partners:
ANO22747.1
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.953
thrS
threonine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.915
cysM
Cysteine synthase B; Catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.913
cbs_2
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.879
ANO26884.1
Pyridoxal-5'-phosphate-dependent protein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.856
serS
serine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.850
pheT
phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.817
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
       0.795
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.795
leuS_1
leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.775
Your Current Organism:
Mycobacteroides abscessus
NCBI taxonomy Id: 36809
Other names: ATCC 19977, CCUG 20993, CIP 104536, DSM 44196, JCM 13569, M. abscessus, Mycobacterium abscessus, Mycobacterium chelonae subsp. abscessus, Mycobacterium chelonei subsp. abscessus, NCTC 13031, strain Hauduroy L948
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