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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANO22871.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)    
Predicted Functional Partners:
purA_1
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 0.995
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.990
purH_1
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.989
apt
Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.973
ANO25717.1
Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.967
adoK_2
Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.942
argH
Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.915
purD_1
Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.909
purK
5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
  
 0.863
guaA
Glutamine-hydrolyzing GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.863
Your Current Organism:
Mycobacteroides abscessus
NCBI taxonomy Id: 36809
Other names: ATCC 19977, CCUG 20993, CIP 104536, DSM 44196, JCM 13569, M. abscessus, Mycobacterium abscessus, Mycobacterium chelonae subsp. abscessus, Mycobacterium chelonei subsp. abscessus, NCTC 13031, strain Hauduroy L948
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