Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANO22958.1DNA helicase; Phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)    
Predicted Functional Partners:
dnaG
DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.841
ANO22957.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
dnaA
Chromosomal replication initiation protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.713
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.672
dnaE
DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.664
pcrA_1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.615
ANO26759.1
DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.608
dnaX
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.592
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
     0.579
dnaN
DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.558
Your Current Organism:
Mycobacteroides abscessus
NCBI taxonomy Id: 36809
Other names: ATCC 19977, CCUG 20993, CIP 104536, DSM 44196, JCM 13569, M. abscessus, Mycobacterium abscessus, Mycobacterium chelonae subsp. abscessus, Mycobacterium chelonei subsp. abscessus, NCTC 13031, strain Hauduroy L948
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