Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
homHomoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)    
Predicted Functional Partners:
ANO23540.1
Homoserine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
lysC
Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.995
ANO23539.1
Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.993
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 0.986
metX
Homoserine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.974
metH_3
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.972
lysA_1
Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.947
ANO27162.1
4-hydroxy-tetrahydrodipicolinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.938
dapA
Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family.
  
 
 0.917
metB
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.904
Your Current Organism:
Mycobacteroides abscessus
NCBI taxonomy Id: 36809
Other names: ATCC 19977, CCUG 20993, CIP 104536, DSM 44196, JCM 13569, M. abscessus, Mycobacterium abscessus, Mycobacterium chelonae subsp. abscessus, Mycobacterium chelonei subsp. abscessus, NCTC 13031, strain Hauduroy L948
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