Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
estB_3Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)    
Predicted Functional Partners:
estB_1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.603
pyrC
Dihydroorotase; Catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.554
carA
Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family.
       0.533
pyrB
Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
       0.533
ANO27071.1
Bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.533
ANO24617.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
carB
Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.527
estB_4
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.453
pyrF
Hypothetical protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). Belongs to the OMP decarboxylase family. Type 2 subfamily.
       0.437
ANO25966.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.423
Your Current Organism:
Mycobacteroides abscessus
NCBI taxonomy Id: 36809
Other names: ATCC 19977, CCUG 20993, CIP 104536, DSM 44196, JCM 13569, M. abscessus, Mycobacterium abscessus, Mycobacterium chelonae subsp. abscessus, Mycobacterium chelonei subsp. abscessus, NCTC 13031, strain Hauduroy L948
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