ANO24698.1 protein (Mycobacteroides abscessus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

ANO24698.1

Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)

Predicted Functional Partners:

ANO24697.1

0.773

ubiE_2

0.743

ANO26050.1

0.666

ANO24699.1

0.586

ANO27086.1

0.532

ANO24700.1

0.532

ANO23935.1

0.515

rebM_2

0.505

ycgJ_1

0.466

ycgJ_2

0.407

Your Current Organism:

Mycobacteroides abscessus

NCBI taxonomy Id: 36809
Other names: ATCC 19977, CCUG 20993, CIP 104536, DSM 44196, JCM 13569, M. abscessus, Mycobacterium abscessus, Mycobacterium chelonae subsp. abscessus, Mycobacterium chelonei subsp. abscessus, NCTC 13031, strain Hauduroy L948

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANO23935.1	ANO24698.1	BAB79_10305	BAB79_14825	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.515
ANO23935.1	ubiE_2	BAB79_10305	BAB79_16955	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ubiquinone biosynthesis methyltransferase UbiE; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.538
ANO23935.1	ycgJ_1	BAB79_10305	BAB79_07340	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.493
ANO24697.1	ANO24698.1	BAB79_14820	BAB79_14825	Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
ANO24697.1	ANO24699.1	BAB79_14820	BAB79_14830	Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.586
ANO24697.1	ANO24700.1	BAB79_14820	BAB79_14840	Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.532
ANO24697.1	ANO27086.1	BAB79_14820	BAB79_14835	Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.532
ANO24698.1	ANO23935.1	BAB79_14825	BAB79_10305	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.515
ANO24698.1	ANO24697.1	BAB79_14825	BAB79_14820	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
ANO24698.1	ANO24699.1	BAB79_14825	BAB79_14830	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.586
ANO24698.1	ANO24700.1	BAB79_14825	BAB79_14840	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.532
ANO24698.1	ANO26050.1	BAB79_14825	BAB79_22970	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.666
ANO24698.1	ANO27086.1	BAB79_14825	BAB79_14835	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.532
ANO24698.1	rebM_2	BAB79_14825	BAB79_00095	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.505
ANO24698.1	ubiE_2	BAB79_14825	BAB79_16955	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ubiquinone biosynthesis methyltransferase UbiE; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.743
ANO24698.1	ycgJ_1	BAB79_14825	BAB79_07340	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.466
ANO24698.1	ycgJ_2	BAB79_14825	BAB79_19010	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407
ANO24699.1	ANO24697.1	BAB79_14830	BAB79_14820	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.586
ANO24699.1	ANO24698.1	BAB79_14830	BAB79_14825	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.586
ANO24699.1	ANO24700.1	BAB79_14830	BAB79_14840	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.697

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Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.913

expected number of edges:

26

PPI enrichment p-value:

0.464

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 272

1.7

4.24

8.45e-16

GO:0032543

Mitochondrial translation

5 of 43

2.16

3.53

4.14e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 152

1.95

6.09

7.34e-19

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005761

Mitochondrial ribosome

11 of 61

2.35

9.44

3.08e-23

GO:0005762

Mitochondrial large ribosomal subunit

9 of 33

2.53

8.95

1.05e-19

GO:0044391

Ribosomal subunit

11 of 140

1.99

6.52

5.46e-20

GO:0098798

Mitochondrial protein-containing complex

11 of 173

1.9

5.86

2.20e-19

GO:0005763

Mitochondrial small ribosomal subunit

2 of 24

2.01

1.14

0.0064

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6472

Organellar ribosome

11 of 64

2.33

9.15

1.14e-22

CL:6476

Organellar ribosome

6 of 22

2.53

5.66

5.68e-12

CL:6546

Organellar large ribosomal subunit, and Ribosomal protein S9

5 of 21

2.47

4.46

1.69e-09

CL:6504

Mixed, incl. Ribosomal protein L25/L23, and Ribosomal protein L30p/L7e

2 of 5

2.7

1.48

0.0020

CL:6549

Mixed, incl. Ribosomal protein S9, and Ribosomal protein L25/L23

2 of 6

2.62

1.43

0.0024

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

7 of 177

1.69

3.02

3.43e-09

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

11 of 259

1.72

4.45

1.38e-16

MAP-392499

Metabolism of proteins

11 of 969

1.15

1.67

1.15e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005762

Mitochondrial large ribosomal subunit

9 of 32

2.54

9.03

8.28e-20

GOCC:0005761

Mitochondrial ribosome

11 of 69

2.3

8.96

1.34e-22

GOCC:0044391

Ribosomal subunit

11 of 146

1.97

6.38

7.99e-20

GOCC:0098798

Mitochondrial protein complex

11 of 160

1.93

6.12

1.05e-19

GOCC:0005763

Mitochondrial small ribosomal subunit

2 of 36

1.84

0.92

0.0165

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

6 of 106

1.85

3.12

2.79e-08

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