Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABN56300.1RNAse III; PFAM: ribonuclease III; double-stranded RNA binding domain protein; KEGG: sco:SCO5572 ribonuclease III. (258 aa)    
Predicted Functional Partners:
ABN55972.1
RNAse III; PFAM: ribonuclease III; KEGG: mhu:Mhun_1116 ribonuclease III.
  
  
  0.950
ABN57422.1
RNAse III; PFAM: ribonuclease III; KEGG: aha:AHA_0800 ribonuclease III.
  
  
 
0.918
ABN56299.1
Protein of unknown function DUF362; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF362; KEGG: dsy:DSY4491 hypothetical protein.
       0.792
rpl2
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
 0.791
rps12
SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
  
 
 0.789
rpl15
LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
 0.785
rpl22
LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.779
rpl13
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.778
rps5
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.775
rps2
PFAM: ribosomal protein S2; KEGG: mhu:Mhun_2892 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.772
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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