STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABN56484.1AMP phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. (507 aa)    
Predicted Functional Partners:
ABN56485.1
KEGG: mhu:Mhun_2261 hypothetical protein.
       0.913
ABN57993.1
Ribose 1,5-bisphosphate isomerase; KEGG: mhu:Mhun_2314 putative translation initiation factor, aIF-2BII; TIGRFAM: putative translation initiation factor, aIF-2BII family; eIF-2B alpha/beta/delta-related uncharacterized proteins; PFAM: initiation factor 2B related; Belongs to the eIF-2B alpha/beta/delta subunits family.
 
  
 0.822
hpt
Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
 
   
 0.728
rpiA
Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
 0.666
thyA
Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
     
 0.661
ABN57021.1
PFAM: purine phosphorylase, family 2; KEGG: mhu:Mhun_1049 purine phosphorylase, family 2.
 
   
 0.649
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
 
   
 0.625
ABN56792.1
Cytidine kinase / inosine-guanosine kinase; PFAM: PfkB domain protein; KEGG: mhu:Mhun_0077 PfkB; Belongs to the carbohydrate kinase PfkB family.
    
 0.619
rbcL
Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
 
   
 0.619
ABN56460.1
PFAM: pyruvate kinase; KEGG: mba:Mbar_A0175 pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.572
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.