Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
ABN56568.1TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. (156 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.999
ABN56570.1
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: mhu:Mhun_1797 3-isopropylmalate dehydrogenase.
 
 0.999
ABN56566.1
2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mhu:Mhun_1801 pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.998
leuC-2
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.985
ABN56569.1
KEGG: mhu:Mhun_1798 hypothetical protein.
       0.936
ABN57873.1
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: mhu:Mhun_2363 3-isopropylmalate dehydrogenase.
 
 0.932
ABN56563.1
tRNA(Ile2) 2-agmatinylcytidine synthetase; PFAM: domain of unknown function DUF1743; KEGG: mhu:Mhun_1804 hypothetical protein.
  
    0.926
ABN56565.1
KEGG: mhu:Mhun_1802 indolepyruvate ferredoxin oxidoreductase alpha and beta subunits-like.
       0.924
cimA
(R)-citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.861
ABN57598.1
2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: mhu:Mhun_2360 pyruvate carboxyltransferase.
 
 
 0.860
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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