Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
ABN56940.1PFAM: nickel-dependent hydrogenase, large subunit; KEGG: det:DET0615 hydrogenase, group 3, VhuA subunit, putative; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (455 aa)    
Predicted Functional Partners:
ABN56555.1
PFAM: methyl-viologen-reducing hydrogenase, delta subunit; KEGG: mhu:Mhun_1842 methyl-viologen-reducing hydrogenase, delta subunit.
 
 0.999
ABN56941.1
PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: mka:MK0267 coenzyme F420-reducing hydrogenase, gamma subunit.
 
 0.999
ABN56556.1
CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.998
ABN56558.1
CoB--CoM heterodisulfide reductase subunit C; KEGG: mhu:Mhun_1836 4Fe-4S ferredoxin, iron-sulfur binding.
 
 0.996
ABN56557.1
CoB--CoM heterodisulfide reductase subunit B; PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: mhu:Mhun_1837 protein of unknown function DUF224, cysteine-rich region.
 
 0.995
ABN57620.1
4Fe-4S ferredoxin, iron-sulfur binding domain protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.980
ABN58099.1
Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: mhu:Mhun_2330 coenzyme F420 hydrogenase.
 
 
 0.964
hypA
Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.947
ABN58100.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: mhu:Mhun_2329 coenzyme F420 hydrogenase/dehydrogenase beta subunit-like.
  
 
 0.939
ABN56947.1
TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein; KEGG: mac:MA1144 F420-nonreducing hydrogenase II.
 
 
 0.915
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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