node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABN56568.1 | ABN57003.1 | Memar_0635 | Memar_1070 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. | KEGG: mhu:Mhun_1242 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein. | 0.631 |
ABN56568.1 | ABN57004.1 | Memar_0635 | Memar_1071 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: mba:Mbar_A0219 acetolactate synthase small subunit. | 0.844 |
ABN56568.1 | ABN57856.1 | Memar_0635 | Memar_1930 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. | Pyruvate oxidase; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mhu:Mhun_0630 thiamine pyrophosphate enzyme-like TPP-binding; Belongs to the TPP enzyme family. | 0.634 |
ABN56568.1 | cimA | Memar_0635 | Memar_1069 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. | (R)-citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.892 |
ABN56568.1 | ilvC | Memar_0635 | Memar_2172 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.900 |
ABN56568.1 | ilvE | Memar_0635 | Memar_1735 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.417 |
ABN56568.1 | leuC | Memar_0635 | Memar_0634 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.999 |
ABN56568.1 | leuC-2 | Memar_0635 | Memar_1949 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.992 |
ABN56568.1 | leuD | Memar_0635 | Memar_1948 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.533 |
ABN56777.1 | ABN57003.1 | Memar_0844 | Memar_1070 | 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_0092 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | KEGG: mhu:Mhun_1242 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein. | 0.937 |
ABN56777.1 | ABN57004.1 | Memar_0844 | Memar_1071 | 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_0092 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: mba:Mbar_A0219 acetolactate synthase small subunit. | 0.932 |
ABN56777.1 | ABN57856.1 | Memar_0844 | Memar_1930 | 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_0092 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | Pyruvate oxidase; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mhu:Mhun_0630 thiamine pyrophosphate enzyme-like TPP-binding; Belongs to the TPP enzyme family. | 0.922 |
ABN56777.1 | cimA | Memar_0844 | Memar_1069 | 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_0092 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | (R)-citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.846 |
ABN56777.1 | leuC-2 | Memar_0844 | Memar_1949 | 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_0092 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.809 |
ABN56777.1 | leuD | Memar_0844 | Memar_1948 | 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_0092 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.810 |
ABN57003.1 | ABN56568.1 | Memar_1070 | Memar_0635 | KEGG: mhu:Mhun_1242 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein. | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: mhu:Mhun_1799 3-isopropylmalate dehydratase, small subunit. | 0.631 |
ABN57003.1 | ABN56777.1 | Memar_1070 | Memar_0844 | KEGG: mhu:Mhun_1242 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein. | 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_0092 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.937 |
ABN57003.1 | ABN57004.1 | Memar_1070 | Memar_1071 | KEGG: mhu:Mhun_1242 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: mba:Mbar_A0219 acetolactate synthase small subunit. | 0.999 |
ABN57003.1 | ABN57856.1 | Memar_1070 | Memar_1930 | KEGG: mhu:Mhun_1242 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein. | Pyruvate oxidase; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mhu:Mhun_0630 thiamine pyrophosphate enzyme-like TPP-binding; Belongs to the TPP enzyme family. | 0.829 |
ABN57003.1 | cimA | Memar_1070 | Memar_1069 | KEGG: mhu:Mhun_1242 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein. | (R)-citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.997 |