Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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co-expression
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ABN57590.1PFAM: protein of unknown function DUF99; KEGG: mtp:Mthe_0335 protein of unknown function DUF99; Belongs to the UPF0215 family. (197 aa)    
Predicted Functional Partners:
ABN57329.1
peptidyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099; KEGG: mhu:Mhun_0809 aminoacyl-tRNA hydrolase.
 
     0.685
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
       0.662
ABN57589.1
PFAM: glycosyl transferase, family 2; KEGG: mac:MA4330 dolichyl-phosphate beta-D-mannosyltransferase.
 
     0.647
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
     0.643
ABN57324.1
DNA-directed RNA polymerase, subunit M; TIGRFAM: transcription factor S; PFAM: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; KEGG: afu:AF1235 DNA-directed RNA polymerase subunit M; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
 
     0.626
ABN57838.1
PFAM: CutA1 divalent ion tolerance protein; KEGG: bbr:BB0060 putative periplasmic divalent cation tolerance protein.
       0.622
ABN58257.1
TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: sai:Saci_0159 uracil DNA glycosylase superfamily protein.
       0.622
tiaS
tRNA(Ile2) 2-agmatinylcytidine synthetase; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.618
ABN58091.1
KEGG: mhu:Mhun_2336 RNA polymerase, dimerisation.
       0.576
ABN57772.1
Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
 
     0.573
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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