Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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eif6Translation initiation factor 6 (aeIF-6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (220 aa)    
Predicted Functional Partners:
rpl31e
PFAM: Ribosomal protein L31e; KEGG: mhu:Mhun_3019 ribosomal protein L31e; Belongs to the eukaryotic ribosomal protein eL31 family.
  
 
 0.999
rpl18a
PFAM: Ribosomal LX protein.
  
 
 0.998
rps19e
SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
 
 
 0.994
rpl3
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 0.986
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 
 0.986
ABN57898.1
PFAM: DNA-binding TFAR19-related protein; KEGG: mhu:Mhun_3016 DNA-binding TFAR19-related protein; Belongs to the PDCD5 family.
 
    0.985
rpl11
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
 
 0.981
rpl21e
PFAM: ribosomal protein L21e; KEGG: mhu:Mhun_3026 ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
   0.980
rpl39e
PFAM: ribosomal protein L39e; KEGG: mbu:Mbur_0115 ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family.
  
  
 0.979
rpl1
LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
 
 
 0.975
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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