Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ABN57907.1KEGG: mhu:Mhun_1739 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. (651 aa)    
Predicted Functional Partners:
ABN58049.1
PFAM: response regulator receiver; KEGG: gme:Gmet_2827 response regulator receiver domain protein (CheY-like).
 
 
 0.758
ABN57071.1
KEGG: mhu:Mhun_1958 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
   
 0.684
ABN57285.1
Signal transduction histidine kinase, nitrogen specific, NtrB; KEGG: sat:SYN_02339 transcriptional regulator GerE family; TIGRFAM: PAS sensor protein; PFAM: histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
   
 0.634
ABN56229.1
PFAM: response regulator receiver; KEGG: mhu:Mhun_1618 response regulator receiver domain protein (CheY-like).
 
 
 0.589
ABN57950.1
PFAM: response regulator receiver; KEGG: mhu:Mhun_2638 response regulator receiver domain protein (CheY-like).
 
 
 
 0.568
ABN56354.1
TIGRFAM: PAS sensor protein; PFAM: histidine kinase A domain protein domain protein; PAS fold-4 domain protein; KEGG: mhu:Mhun_1147 putative PAS/PAC sensor protein.
 
     0.559
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 0.547
ABN56805.1
KEGG: mhu:Mhun_1309 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 
0.516
ABN56878.1
PFAM: response regulator receiver; KEGG: mhu:Mhun_0108 response regulator receiver domain protein (CheY-like).
 
 
 
 0.507
gap
KEGG: mhu:Mhun_2462 glyceraldehyde-3-phosphate dehydrogenase, type II; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase.
  
 
 0.506
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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