STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABN57908.1PFAM: Protein of unknown function DUF371; KEGG: mhu:Mhun_2615 protein of unknown function DUF371. (141 aa)    
Predicted Functional Partners:
ABN57909.1
KEGG: mhu:Mhun_2616 hypothetical protein.
 
     0.814
rnp4
Ribonuclease P protein subunit Rpp21; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
 
     0.706
tfe
Transcription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...]
  
   
 0.622
rps17e
KEGG: mhu:Mhun_1491 30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
       0.570
pcm
protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
       0.570
nusA-2
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
  
     0.551
pfdA
Prefoldin, alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
     0.531
ABN57443.1
PFAM: zinc finger, SWIM domain protein; KEGG: mhu:Mhun_0038 zinc finger, SWIM-type.
  
     0.528
ABN57941.1
KEGG: mhu:Mhun_2823 phosphoesterase, DHHA1.
  
     0.516
ABN58167.1
Protein of unknown function DUF359; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
     0.515
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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