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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpF-2PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mma:MM3314 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (220 aa)    
Predicted Functional Partners:
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.995
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
 
 
 0.994
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.937
ABN56006.1
PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein; KEGG: gsu:GSU2383 anthranilate synthase component I.
 
  
 0.931
ABN56007.1
Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: neu:NE0014 panthranilate synthase component II (glutamine amido-transferase) protein.
 
  
 0.924
trpB-2
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.919
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mhu:Mhun_1789 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family.
  
  
 
0.915
ABN57229.1
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mhu:Mhun_1032 prephenate dehydratase.
 
  
 0.567
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.477
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
  
 0.456
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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