STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0004PFAM: major facilitator superfamily MFS_1; KEGG: pfu:PF0443 putative membrane transport protein. (428 aa)    
Predicted Functional Partners:
Tpen_0003
KEGG: pab:PAB2176 hypothetical 2-acetyl-1-alkylglycerophosph ocholine esterase.
 
    0.835
Tpen_0002
Cellulase; PFAM: peptidase M18, aminopeptidase I; peptidase M20; peptidase M42 family protein; KEGG: gka:GK2713 hypothetical protein.
       0.525
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
 
    0.427
Tpen_0076
6-phosphogluconate dehydrogenase, NAD-binding; PFAM: oxidoreductase domain protein; NADP oxidoreductase, coenzyme F420-dependent; homoserine dehydrogenase, NAD-binding; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: bxe:Bxe_A0271 oxidoreductase.
 
    0.418
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
Server load: low (12%) [HD]