STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0190TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: tko:TK2076 probable formate dehydrogenase, alpha subunit. (685 aa)    
Predicted Functional Partners:
Tpen_0189
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: tko:TK2077 4Fe-4S cluster-binding protein.
 
 0.997
Tpen_1409
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE2661 formate dehydrogenase beta subunit.
 
 0.983
Tpen_1423
PFAM: formylmethanofuran dehydrogenase, subunit E region; KEGG: pho:PH1238 hypothetical protein.
  
 
 0.926
Tpen_1766
Sulfide dehydrogenase (flavoprotein) subunit SudA; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE3227 glutamate synthase small subunit.
    
 0.920
Tpen_0594
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: chy:CHY_2406 putative reductase, iron-sulfur cluster-binding subunit.
  
 
 0.919
Tpen_1408
Formate dehydrogenase alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: pai:PAE2662 formate dehydrogenase alpha subunit.
  
  
 
0.917
Tpen_1410
KEGG: pai:PAE2660 formate dehydrogenase, cytochrome b556 subunit (formate dehydrogenase gamma subunit).
    
 0.908
Tpen_0143
NADPH:sulfur oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: afu:AF0395 NADH oxidase (NoxA-2).
    
 0.905
Tpen_0183
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; NADH dehydrogenase (ubiquinone), 30 kDa subunit; KEGG: mta:Moth_2186 NADH dehydrogenase (ubiquinone), 30 kDa subunit.
    
 0.881
Tpen_1122
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE2860 molybdopterin oxidoreductase, iron-sulfur binding subunit.
 
 
 0.854
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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