STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpl1Large subunit ribosomal protein l1; Binds directly to 23S rRNA. Probably involved in E site tRNA release (225 aa)    
Predicted Functional Partners:
rpl10
Large subunit ribosomal protein l10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
 
 0.999
rpl11
Large subunit ribosomal protein l11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
 
 0.999
rps19
Small subunit ribosomal protein s19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
 
 
 0.999
rpl2
Large subunit ribosomal protein l2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome
 
 0.999
rpl23
Large subunit ribosomal protein l23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome
  
 0.999
rpl3
Large subunit ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
 
 0.999
rpl15
Large subunit ribosomal protein l15; Binds to the 23S rRNA
 
 0.999
rpl30
TIGRFAM: ribosomal protein L30P; PFAM: ribosomal protein L30; KEGG: neq:NEQ311 LSU ribosomal protein L30P
 
 0.999
rps5
Small subunit ribosomal protein s5; With S4 and S12 plays an important role in translational accuracy
 
 0.999
rpl18
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
  
 0.999
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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