STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0311PFAM: tRNA intron endonuclease, catalytic-like; tRNA intron endonuclease domain protein; KEGG: pab:PAB1099 tRNA intron endonuclease. (193 aa)    
Predicted Functional Partners:
Tpen_0619
TIGRFAM: tRNA intron endonuclease; PFAM: tRNA intron endonuclease, catalytic-like; KEGG: ape:APE1646 tRNA intron endonuclease.
  
 
 
 0.834
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
 
   0.780
Tpen_0195
KEGG: mka:MK0077 predicted GTPase or GTP-binding protein.
    
 0.750
Tpen_0310
PFAM: PUA domain containing protein; KEGG: pai:PAE1626 PUA domain protein.
       0.687
Tpen_0943
Protein of unknown function DUF650, N-terminal domain; Involved in DNA damage repair.
  
     0.535
Tpen_0312
TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; KEGG: sai:Saci_0221 molybdopterin-binding domain protein.
       0.515
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
       0.515
Tpen_0463
PFAM: Protein of unknown function UPF0147; KEGG: ape:APES069 hypothetical protein; Belongs to the UPF0147 family.
  
     0.502
Tpen_0774
PFAM: protein of unknown function DUF75; KEGG: ape:APE0104 hypothetical protein.
  
     0.484
cca
tRNA adenylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
 
   
 0.482
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.