STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0318TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein; KEGG: pab:PAB1560 hydrogenase expression/formation regulatory protein. (755 aa)    
Predicted Functional Partners:
Tpen_1613
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mth:MTH205 hydrogenase expression/formation protein HypE.
 
 
 0.938
Tpen_1615
PFAM: hydrogenase formation HypD protein; KEGG: sfu:Sfum_4014 hydrogenase expression/formation protein HypD.
 
  
 0.897
Tpen_1667
PFAM: AIR synthase related protein domain protein; KEGG: tko:TK1032 hydrogenase expression/formation protein HypE.
 
 
 0.829
Tpen_0592
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: sma:SAV7367 putative cytochrome C3-like hydrogenase (NiFeSe) large chain.
 
 
 
 0.804
Tpen_1029
PFAM: AIR synthase related protein domain protein; KEGG: mta:Moth_0697 AIR synthase related protein-like.
  
 
 0.804
Tpen_0591
TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: Nickel-iron dehydrogenase small subunit, N-terminal domain protein; KEGG: fal:FRAAL2392 uptake hydrogenase small subunit precursor (hydrogenlyase) (membrane-bound hydrogenase small subunit).
 
 
 
 0.765
Tpen_1614
Hypothetical protein.
  
 
 0.685
hypA
Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.643
Tpen_0319
PFAM: peptidase M20; peptidase M28; KEGG: bld:BLi04074 YwaD.
       0.561
Tpen_0317
KEGG: sto:ST0946 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase.
   
   0.499
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.