Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpen_0366PFAM: regulatory protein, AsnC/Lrp family; KEGG: pab:PAB0125 transcriptional regulatory protein, AsnC family. (154 aa)    
Predicted Functional Partners:
Tpen_0688
TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; Protein of unknown function DUF357; KEGG: ape:APE2281 hypothetical protein.
  
    0.694
Tpen_0365
PFAM: putative RNA methylase; putative methyltransferase; KEGG: pai:PAE3486 hypothetical protein.
       0.521
Tpen_0927
TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative; KEGG: afu:AF1736 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
     
 0.512
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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