STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfdAPrefoldin, alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (129 aa)    
Predicted Functional Partners:
pfdB
Prefoldin beta- domain protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
 0.999
rpl18a
PFAM: Ribosomal LX protein; KEGG: ape:APE1084a S ribosomal protein LX.
  
    0.841
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.819
rpl31e
PFAM: Ribosomal protein L31e; KEGG: pai:PAE3095 ribosomal protein L31; Belongs to the ribosomal protein L31e family.
  
    0.792
Tpen_0471
PFAM: DNA-binding TFAR19-related protein; KEGG: ape:APE1088a DNA-binding protein; Belongs to the PDCD5 family.
  
   0.779
Tpen_0291
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: pai:PAE3273 thermosome (chaperonin) beta subunit.
   
 
 0.773
Tpen_0693
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: pai:PAE2117 thermosome (chaperonin) alpha subunit.
   
 
 0.773
rpl5
LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
 
    0.737
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: pfu:PF2054 30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
   
    0.677
rps17e
PFAM: Ribosomal protein S17e; KEGG: pai:PAE0804 ribosomal protein S17; Belongs to the eukaryotic ribosomal protein eS17 family.
 
    0.633
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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