STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif2gTranslation initiation factor 2 subunit gamma (aeIF-2g); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (423 aa)    
Predicted Functional Partners:
eif2b
Translation initiation factor 2 subunit beta (aeIF-2b); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
  
 0.999
Tpen_0642
PFAM: RNA binding S1 domain protein; translation initiation factor 2, alpha subunit; KEGG: mka:MK0419 translation initiation factor eIF2-alpha.
  
 0.992
eif1a
Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
 
 0.979
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
 0.979
rps6e
PFAM: ribosomal protein S6e; KEGG: mka:MK1446 ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family.
 
 0.977
rps5
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 0.976
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: pfu:PF2054 30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
 
 0.973
rps15
PFAM: ribosomal protein S15; Ribosomal S13S15-like; KEGG: mka:MK1593 ribosomal protein S15P/S13E.
 
 0.970
rps4e
PFAM: RNA-binding S4 domain protein; Ribosomal protein S4E-like; Ribosomal protein S4E, central; KEGG: ape:APE0356 30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family.
  
 0.968
rps2
PFAM: ribosomal protein S2; KEGG: pai:PAE0817 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 0.967
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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