node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tpen_0699 | Tpen_0709 | Tpen_0699 | Tpen_0709 | PFAM: Protein of unknown function DUF373; KEGG: pab:PAB1241 hypothetical protein. | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.529 |
Tpen_0699 | ribK | Tpen_0699 | Tpen_0098 | PFAM: Protein of unknown function DUF373; KEGG: pab:PAB1241 hypothetical protein. | Protein of unknown function DUF120; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.630 |
Tpen_0699 | tiaS | Tpen_0699 | Tpen_0604 | PFAM: Protein of unknown function DUF373; KEGG: pab:PAB1241 hypothetical protein. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.519 |
Tpen_0706 | Tpen_0707 | Tpen_0706 | Tpen_0707 | PFAM: PUA domain containing protein; KEGG: mth:MTH176 tRNA-guanine transglycosylase. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | 0.575 |
Tpen_0706 | Tpen_0709 | Tpen_0706 | Tpen_0709 | PFAM: PUA domain containing protein; KEGG: mth:MTH176 tRNA-guanine transglycosylase. | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.745 |
Tpen_0706 | hflX | Tpen_0706 | Tpen_0708 | PFAM: PUA domain containing protein; KEGG: mth:MTH176 tRNA-guanine transglycosylase. | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.575 |
Tpen_0706 | ribK | Tpen_0706 | Tpen_0098 | PFAM: PUA domain containing protein; KEGG: mth:MTH176 tRNA-guanine transglycosylase. | Protein of unknown function DUF120; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.456 |
Tpen_0706 | tfe | Tpen_0706 | Tpen_0710 | PFAM: PUA domain containing protein; KEGG: mth:MTH176 tRNA-guanine transglycosylase. | Transcription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...] | 0.575 |
Tpen_0706 | tiaS | Tpen_0706 | Tpen_0604 | PFAM: PUA domain containing protein; KEGG: mth:MTH176 tRNA-guanine transglycosylase. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.574 |
Tpen_0707 | Tpen_0706 | Tpen_0707 | Tpen_0706 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | PFAM: PUA domain containing protein; KEGG: mth:MTH176 tRNA-guanine transglycosylase. | 0.575 |
Tpen_0707 | Tpen_0709 | Tpen_0707 | Tpen_0709 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.819 |
Tpen_0707 | hflX | Tpen_0707 | Tpen_0708 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.872 |
Tpen_0707 | tfe | Tpen_0707 | Tpen_0710 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | Transcription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...] | 0.837 |
Tpen_0709 | Tpen_0699 | Tpen_0709 | Tpen_0699 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | PFAM: Protein of unknown function DUF373; KEGG: pab:PAB1241 hypothetical protein. | 0.529 |
Tpen_0709 | Tpen_0706 | Tpen_0709 | Tpen_0706 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | PFAM: PUA domain containing protein; KEGG: mth:MTH176 tRNA-guanine transglycosylase. | 0.745 |
Tpen_0709 | Tpen_0707 | Tpen_0709 | Tpen_0707 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. | 0.819 |
Tpen_0709 | Tpen_0774 | Tpen_0709 | Tpen_0774 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | PFAM: protein of unknown function DUF75; KEGG: ape:APE0104 hypothetical protein. | 0.611 |
Tpen_0709 | Tpen_0882 | Tpen_0709 | Tpen_0882 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.530 |
Tpen_0709 | Tpen_0943 | Tpen_0709 | Tpen_0943 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Protein of unknown function DUF650, N-terminal domain; Involved in DNA damage repair. | 0.516 |
Tpen_0709 | hflX | Tpen_0709 | Tpen_0708 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.852 |