STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0717PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: nha:Nham_1304 oxidoreductase-like. (343 aa)    
Predicted Functional Partners:
Tpen_0895
PFAM: transferase hexapeptide repeat containing protein; KEGG: pab:PAB0773 putative acetyltransferase.
 
  
 0.908
Tpen_0110
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: pai:PAE2053 pleiotropic regulatory protein, conjectural; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.842
Tpen_0820
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: tma:TM0416 D-tagatose 3-epimerase-related protein.
  
  
 0.766
Tpen_0839
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: mta:Moth_2270 xylose isomerase-like TIM barrel.
  
  
 0.766
Tpen_1349
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: rba:RB7382 hypothetical protein.
  
  
 0.766
Tpen_1114
Galactokinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein; KEGG: pai:PAE1185 galactokinase.
  
 
 0.763
Tpen_1715
PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: pfu:PF0794 UDP-N-acetylglucosamine 2-epimerase.
  
  
 0.673
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
 
 0.511
Tpen_1215
PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: reh:H16_B0034 UDP-N-acetyl-D-mannosamine 6-dehydrogenase.
  
  
 0.496
Tpen_0612
PFAM: PfkB domain protein; KEGG: chu:CHU_0279 probable carbohydrate kinase, PfkB family.
  
  
 0.491
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.