STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppSUndecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (268 aa)    
Predicted Functional Partners:
Tpen_0606
Geranyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: pai:PAE1013 dimethylallyltranstransferase / geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
 
 
 0.966
Tpen_0864
Peptidase M50; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: pfu:PF0167 metalloprotease.
 
  
 0.896
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
  
    0.868
pyrH
Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.863
Tpen_1163
CTP synthase; PFAM: glutamine amidotransferase class-I; CTP synthase; KEGG: pho:PH1792 CTP synthase.
  
    0.798
Tpen_0555
PFAM: putative RNA methylase; methyltransferase small; Methyltransferase type 11; KEGG: ape:APE0557 hypothetical protein.
  
    0.790
Tpen_0412
PFAM: glycosyl transferase, family 4; KEGG: mth:MTH590 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphstransferase.
 
  
 0.701
Tpen_0764
TIGRFAM: putative hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase, N-terminal domain; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; KEGG: pfu:PF0972 3-oxoacyl-[acyl-carrier-protein] synthase III; Belongs to the thiolase-like superfamily. UPF0219 family.
   
 
 0.648
Tpen_0765
PFAM: Thiolase; KEGG: pab:PAB0907 3-ketoacyl-CoA thiolase.
     
 0.601
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
     
 0.585
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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