STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0776PFAM: helix-turn-helix domain protein; KEGG: pai:PAE1638 putative transcriptional regulator. (248 aa)    
Predicted Functional Partners:
Tpen_0764
TIGRFAM: putative hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase, N-terminal domain; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; KEGG: pfu:PF0972 3-oxoacyl-[acyl-carrier-protein] synthase III; Belongs to the thiolase-like superfamily. UPF0219 family.
  
    0.899
Tpen_0765
PFAM: Thiolase; KEGG: pab:PAB0907 3-ketoacyl-CoA thiolase.
  
    0.768
Tpen_0766
PFAM: protein of unknown function DUF35; KEGG: pab:PAB0908 AcaC protein.
  
    0.724
Tpen_0777
PFAM: type II secretion system protein; KEGG: neq:NEQ268 putative flaggella related protein split see NEQ267.
 
     0.659
Tpen_0464
PFAM: Radical SAM domain protein; KEGG: pab:PAB0713 hypothetical protein.
  
     0.625
Tpen_0454
NMD3; PFAM: NMD3; KEGG: pai:PAE1653 hypothetical protein.
  
   
 0.599
Tpen_0699
PFAM: Protein of unknown function DUF373; KEGG: pab:PAB1241 hypothetical protein.
 
     0.596
Tpen_0378
PFAM: helix-turn-helix domain protein; KEGG: afu:AF1787 putative transcriptional regulator.
  
   
 0.564
Tpen_0695
KEGG: mka:MK0399 uncharacterized protein conserved in archaea; Belongs to the UPF0201 family.
  
     0.549
rpl21e
PFAM: ribosomal protein L21e; KEGG: pai:PAE3334 ribosomal protein L21; Belongs to the eukaryotic ribosomal protein eL21 family.
  
     0.548
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.