STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpen_0856TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pai:PAE1558 2-oxoacid ferredoxin oxidoreductase beta subunit. (284 aa)    
Predicted Functional Partners:
Tpen_0857
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tte:TTE0961 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
 0.999
Tpen_1456
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_2992 pyruvate flavodoxin/ferredoxin oxidoreductase-like.
 0.996
Tpen_0573
Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pho:PH0684 pyruvate ferredoxin oxidoreductase, alpha subunit.
 
 0.953
Tpen_0542
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sto:ST1532 pyruvate ferredoxin oxidoreductase, alpha subunit.
 
 0.952
Tpen_0540
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: sto:ST1531 pyruvate ferredoxin oxidoreductase, gamma subunit.
  
 0.951
Tpen_0571
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: tko:TK1978 pyruvate/2-oxoisovalerate: ferredoxin oxidoreductases, common gamma subunit.
  
 0.951
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.934
Tpen_0516
succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; KEGG: pai:PAE2312 succinyl-CoA synthetase beta subunit.
  
 
 0.932
Tpen_0330
PFAM: pyruvate kinase; KEGG: art:Arth_1693 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.925
Tpen_1824
Dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: mba:Mbar_A2696 dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
    
 0.920
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.